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ESR 10: Davide Avagliano
Simulation of Photo-controlled DNA Binding and Damage
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LightDyNAmics Research
Scientific Background
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My aim is to carry out advanced quantum chemical and dynamical simulations on spiropyran derivatives embedded in DNA. After the theoretical design of spiropyran dyes able to efficiently induce DNA photodamage, the goal is to unravelling the underlying mechanisms behind the mode of action of spiropyrans. In particular, I will focus on photo-isomerization, DNA binding, excited-state electron transfer and energy transfer.
Bachelor Degree in Chemistry, “Sapienza University of Rome”
Master of Science in Chemistry, “Sapienza University of Rome” Area of interest: Theoretical Chemistry, Computational Chemistry, Physical Chemistry. |
