I am studying the riboswitch structure and dynamics features by implementing Molecular Mechanics (MM) and Quantum Mechanics (QM) simulations. By comparing MM, QM simulations and the experimental data, I am going to evaluate the nucleic acids force field quality. I will explore more MM and QM techniques on more nucleic acid cases in my further PhD period.
Bachelor’s study: Zhejiang University, China. Majoring in Bioinformatics and having internships on Molecular Dynamics (MD) simulations and docking.
Master’s study: Utrecht University, the Netherlands. Molecular & Cellular Life Sciences program. Having the internship on docking, supervised by Prof. Alexandre Bonvin, and the internship on nucleic acids structure and dynamics study, supervised by Prof. Jiri Sponer.