Guanine Quadruplexes (G4) are four-stranded structures formed by guanine rich DNA sequences. They have been correlated with the oxidative damage which perturbs biological functions. In addition, G4 structures are studied in respect to their applications in molecular electronics and nanotechnologies.
The objective of the research is to study the generation and the reactivity of guanine radicals (including electron holes, important in charge transport) induced by absorption low energy UV radiation by G4. The investigation will involve the use of several experimental and computational techniques:
Diploma in Applied Mathematical and Physical Sciences at National Technical University of Athens(NTUA) (2012-2017)
Nine month internship and Diploma Thesis preparation in “Ionizing Radiation Dose Enhancement Through the Use of Gold Nanoparticles” Institute of Nuclear & Radiological Sciences & Technology, Energy & Safety, National Centre for Scientific Research “NCSR-Demokritos” (2016-2017).Three months internship at the Institute of Medical Radiation Biology, the University of Duisburg-Essen in Germany (2017)