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Introduction Week: DNA Fundamentals

The LightDyNAmics Introduction Week will be held on 21 - 25 January 2019 the Institute for Biostructures and Bioimaging (CNR) in Naples, Italy.  The ESRs will be introduced to their new field of light/soft-matter interaction and will take the vital first steps in forming the key relationships across the LightDyNAmics network. ESRs will be introduced to the basic principles of genetics, DNA and RNA structure.

Programme

Day 1 
  • Presentation of IBB
  • ESR presentations
  • Nucleic Acids, a histroical perspective: from the first understanding of the principle of genetics to the discovery of the duplex structure (L. Vitiglano, IBB-CNR)
  • Basic principles of genetics: DNA/RNA/protein synthesis (M.Müller, LMUM)
Day 2
  • RNA structural conformational behaviour (J. Sponer, MUNI)
  • Basics of the photophysics of the isolated bases: Experiments (T. Gustavsson, CNRS)
  • Basics of the photophysics of Polynucleotides: Experiments (D. Markovitsi, CNRS)
  • Guided Tour of the historic centre of Naples
Day 3
  • Management Board meeting
  • Basics on the photophysics of the isolated bases: Calculations (M. Garavelli, UNIBO)
  • Basics of DNA structure and conformational behaviour: Single strand, Duplex, Quadruplex (J. Plavec, KI)
  • Exercises on genetics, spectrscopy, formation of hydrogen bonds, QM calculations
Day 4
  • Experimental approaches for the characterization of DNA structure and energetics (S. Quinn, UCD)
  • DNA based nanomaterials (S. Quinn, UCD)
  • Basics of the photochemistry of Polynucleotides: Experiments (D. Markovitsi, CNRS)
  • Basics of the photophysics of Polynucleotides: Calculations (F. Santoro, ICCOM-CNR)
  • Team Exercises: Short MD simulations and QM calculations on the photophysics of oligonucleotides
Day 5
  • Intervening with DNA in drug discovery (K. Herlihy, AZ)
  • Basics of the photochemistry of Polynucleotides: Calculations (R. Improta, IBB-CNR)
  • Team Exercises: Short MD simulations and QM calculations on the photochemistry of oligonucleotides

Picture
This project has received funding from the European Union’s Horizon 2020 Research and Innovation Programme under the Marie Sklodowska-Curie grant agreement No 765266.
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  • Project
    • Publications
    • Cartoon
  • Network
    • Beneficiaries
    • Partner Organisations
  • People
    • ESRs
    • Supervisors
  • Training
    • Approach
    • Events >
      • Introduction Week
      • 1st LightDyNAmics Week
      • Technology Training Camp
      • Workshop: Software Solutions for Drug Discovery
  • News