Prof. Jiří Šponer
B6: Department of Structure and Dynamics of Nucleic Acids (CEITEC), Masaryk University, Czech Republic
Computational studies of nucleic acids and their complexes with ligands and proteins, including atomistic classical simulations, advanced quantum-chemical calculations, bioinformatics and hybrid QM/MM methods. Structural molecular biology and biophysics. Physical chemistry of molecular interactions. Current main research topics: 1) RNA structural dynamics, folding and catalysis. 2) Protein-RNA complexes. 3) DNA, with focus on G-quadruplexes. 4) Diverse types of quantum-chemical studies on nucleic acids systems. 5) Origin of life (prebiotic chemistry). 6) Development of DNA and RNA simulation force fields.
Role in LightDyNAmics
Supervisor of ESR5